EPISKIN

EPISKIN, world leader in tissue engineering, offers Human Reconstructed Tissues to the global scientific community – academic and industry – to support research and development activities in Safety and Efficacy

New Project - 2024-12-09T173231.773

In Vitro Test Approach

Based on easy-to-use and validated protocols, EPISKINTM tissue models allow industrial corporations to screen and measure with high precision, the irritation, penetration, metabolism, or efficacy of large number of formulations or actives, to eliminate those that are unsuitable, so that the final (in vivo or clinical) tests can be carried out on a selected few.
New Project - 2024-12-09T173231.773

ISO 9001

EPISKIN has implemented a successfull ISO 9001 quality management system since 1999 to guarantee:
  • Standardization of Production and QC processes.
  • Reproducibility of human reconstructed models.
  • Customer satisfaction.
  • New Project - 2024-12-09T173231.773

    Regulatory context

    A sustainable development of in vitro alternative methods has been done within an ethical and regulatory framework which comprises the following topics: VALIDATIONS Process aimed to confirm that procedures employed for a specific test are suitable for its intended use.


    We provide our worldwide clients RELIABLE AND RELEVANT IN VITRO TOOLS FOR SAFETY AND EFFICACY EVALUATION.

    Based in Lyon, France, we partner with cosmetical, pharmaceutical and chemical industries to develop relevant and reliable safety and efficacy tests. Our models are critical tools to speed up Research and Development phases and to shorten the time to market. Some screening tests are already referenced and validated as alternatives to animal use, and others are in the process of validation.

    Our unique cell culture process allows to industrialize important volumes of in vitro models of reconstructed human tissues with well characterized histology, functionality and ultrastructure features. The production unit has been designed to deliver every week our clients with thousands of human tissues.

    Product Categories

    Reconstructed Human Full Thickness Skin Model

    Reconstructed Human Epidermis

    Human Epidermal Model Langerhans Cells

    Reconstructed Human Pigmented Epidermis

    Human Corneal Epithelium

    Reconstructed Human Oesophageal Epithelium

    Human Oral Epithelium

    Human Gingival Epithelium

    Reconstructed Human Bladder Epithelium

    Human Vaginal Epithelium

    More About EPISKIN

    EPISKIN Corporate Movie - ADVANCED 3D MODELS FOR A BETTER, MORE PREDICTIVE AND MORE ETHICAL SCIENCE

    Our product lines include:

    • Reconstructed human epidermis,
    • Reconstructed human epidermis with melanocytes (different complexions are available from phototype II to VI),
    • Reconstructed human dermis and epidermis: Full Thickness Model
    • Reconstructed Human Corneal Epithelium, Reconstructed Human mucosa: Oral, Gingival, and Vaginal Epithelium.

    All of these models allow the evaluation of raw materials, active ingredients and finished products being either in a solid, liquid, powder, cream or gel form.

    Flyers and Product Guides

    Coming Soon…

    Coming Soon…

    Coming Soon…

    A Comprehensive Array of Multifunctional Cosmetic Claims

    Eye Care, Cosmetic & Herbal Soaps, Skin Care, Hair Care & more

    Scientific References

    FAQ

    Q1. What 3D reconstructed human tissue models does Episkin offer?
    A. Skin irritation, corrosion, phototoxicity, and ocular irritation models.

    Q2. Are Episkin models OECD validated?
    A. Yes. Episkin models comply with OECD guidelines and are widely accepted for regulatory testing.

    Q3. What are the lead times for ordering Episkin tissue models in India?
    A. Standard lead time 4–5 weeks due to production and international shipping constraints.

    Q4. How are Episkin products shipped?
    A. Temperature-controlled express shipping with detailed handling instructions on arrival.

    Q5. How does EPISKIN ensure the quality and reproducibility of its tissue models?
    A. Each EPISKIN tissue batch undergoes stringent quality control for viability, morphology, and barrier function. This ensures consistent, reliable performance and full compliance with OECD and regulatory standards.

    Q6. What applications can EPISKIN tissue models be used for?
    A. EPISKIN models are used in cosmetics, pharmaceuticals, chemicals, and academic research to evaluate skin irritation, corrosion, phototoxicity, genotoxicity, and compound penetration or efficacy.

    Q7. What are the storage and handling requirements for EPISKIN models?
    A. Upon arrival, tissues must be stored at 37°C in a CO₂ incubator and used immediately according to the test protocol provided. They are shipped ready-to-use and should not be frozen.

    Q8. Do EPISKIN models require ethical clearance for testing?
    A. No. EPISKIN models are developed from ethically sourced human keratinocytes and are animal-free, eliminating the need for animal testing or related ethical approvals.

    Q9. Can EPISKIN provide customized testing services or model adaptations?
    A. Yes. EPISKIN offers customized models and testing solutions upon request, including pigmentation, atopic, and reconstructed ocular tissues tailored for specific study needs.

    Didn’t find your answer?
    Ask us now.

    The Krishgen support team strives to provide swift responses and resolution to your queries. Get in touch for a technical question, product query or quote request.