BioIVT
Advance your research with BioIVT's wide range of human and animal biospecimens. All samples are readily available with them in the US and can also be customized to your specifications
Stock Availability
Technologies
Quality
BioIVT is the worldwide leader of biological products to life sciences and pharmaceutical companies.
Here’s what they have to say about working with BioIVT.
They are committed to providing the highest quality human and animal biological matrices, and processing services, as well as excellent customer support.
We provide:
- Customization of all products available
- Knowledgeable and attentive customer service team
- Products delivered in a timely manner, ready for use
- Unconditional product guarantee
- Saturday shipments available
- Same day collection, shipment of time sensitive blood samples, tissues and PBMCs
- Wide variety of biological products available
Product Portfolio
BioIVT's scientists and industry experts can partner with you to develop a custom program of specimens, collection schedules, and testing services to meet your research needs.
ADME Tissues, Fractions and Enzymes
Normal Human and Animal (NHA) Tissues and Fluids
Diseased State (DS) Human and Animal Tissues and Fluids
Complex Therapies
Krishgen stocks hepatocytes, microsomes, plasma, sera and more at our Mumbai warehouse.
Explore available products and lots.
Featured Products
Advance your research with our wide range of human and animal biospecimens.
Our samples are readily available and can also be customized to your specifications.
Product Categories
Biofluids (Blood-derived)
Biofluids (Other)
Media / Reagents / Kits
Cell Products
Molecular Products
Subcellular Fractions & Recombinant Enzymes
Tissue
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Services Offered
More About BioIVT
ADME 101: Drug Metabolism Studies – Metabolic Stability
Metabolic stability influences the oral bioavailability and plasma half-life of a compound. Metabolic stability assays measure intrinsic clearance and determine the extent to which a drug will be metabolized. This study can be conducted in a variety of test systems, which is why it may also be referred to as a hepatocyte stability study, microsomal stability study, etc. This quick overview video discusses:
• Test systems for stability assays
• Stability study endpoints
• Example data in different species
• Considerations for those wanting to conduct stability studies
Technologies
BioIVT's suite of innovative technologies provides our clients with novel methodologies for drug discovery, in vitro diagnostics, and ADME-Tox studies.
Latest Blogs
FAQ
Q1. What ADME-Tox products from BioIVT are available in India?
A. Krishgen supplies BioIVT’s full portfolio of human biospecimens, hepatocytes, subcellular fractions, transporter assays, and ADME-Tox tools for Indian CROs and pharma.
Q2. What ethical sourcing certifications do BioIVT products carry?
A. BioIVT products comply with all applicable U.S. and EU ethical sourcing and informed consent regulations; documentation is available upon request.
Q3. What are the storage and shipping conditions?
A. Cryopreserved products ship on dry ice; other biospecimens on ice packs. Recommended storage conditions are listed on the COA.
Q4. Are BioIVT exosomes or primary cells available on standing order or custom lots?
A. Yes. Krishgen can arrange custom lots or recurring shipments to meet study timelines in India.
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Q6. What are ADME products?
A. ADME products study a drug’s absorption, distribution, metabolism, and excretion to predict behavior, optimize dosing, and assess safety, with BioIVT offering hepatocytes, Kupffer cells, multicellular systems, subcellular fractions, Bactosomes, and recombinant enzymes.
Q7. How does BioIVT ensure quality and ethical sourcing of biospecimens?
A. BioIVT collects human tissues under strict legal and ethical standards from RTOs/OPOs, with oversight by Regulatory and Quality teams and thorough characterization of isolated hepatocytes, cells, and subcellular fractions.
Q8. How do I choose the ideal test system for an in vitro ADME study?
A. The choice depends on research goals, with rigorous validated systems for regulatory submissions (e.g. IND submission) and simpler systems often sufficient for early lead selection.
Q9. What types of human hepatocytes does BioIVT offer?
A. BioIVT provides cryoplateable, cryosuspension, and fresh human hepatocytes, available as single-donor or pooled lots. Specialized options include CryostaX® (single-freeze), TRANSPORTER CERTIFIED® (for transporter studies), and SPHEROID CERTIFIED™ (for 3D hepatic models).
Q10: When should I use hepatocytes versus subcellular fractions?
A. Use whole hepatocytes for integrated metabolism, transporter activity, and long-term culture studies. Subcellular fractions like microsomes, S9, and cytosol are ideal for studying specific metabolic pathways, enzyme inhibition, or intrinsic clearance.
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